Most of the existing neuro-symbolic AI methods focus on the scenario of static knowledge where objects do not change according to a temporal dimension. Temporal neuro-symbolic works are still under explored and are mainly developed for time-interval logic or propositional linear temporal logic. There is a lack of models studying linear temporal logics with predicates that deal with objects whose properties and relations change through the time. We present First-Order Temporal Logic Tensor Networks (FOT-LTN) that is an extension of Logic Tensor Networks (LTN) that fills this gap by considering a linear-temporal dimension. In particular, FOT-LTN joins the syntax of First-Order Linear Temporal Logic with the fuzzy (and real-valued) semantics of LTN obtaining a framework that supports both temporal operators and quantifiers and is totally differentiable. A first evaluation regards a temporal knowledge graph completion task on two synthetic datasets showing better performance of FOT-LTN with respect to dedicated (purely neural) methods.
Agentic assistants capable of proactive, personalized interactions require structured models of user intent and workflow. However, building these models from raw, unstructured screen activity remains an open challenge. We present SERUM, a multi-pass framework that extracts finite…
We introduce implicit machine learning force fields (I-MLFFs), which replace explicit stacks of neural network layers with self-consistent fixed-point equations. In molecular simulations, this formulation enables intermediate representations to be reused across successive timeste…
The reliance on unstructured free text for documenting clinical trial protocols creates a significant barrier to automated reasoning, cohort discovery, and trial simulation. The lack of formal structure obscures critical temporal phenotypes, such as dynamic eligibility criteria a…
Convolutional neural networks (CNNs) are widely used for time-series classification, but their deployment in critical domains requires understanding the temporal and spectral patterns that drive their predictions. Concept extraction (CE) methods identify such patterns by analyzin…
Molecular glue degraders have emerged as a promising strategy for targeted protein degradation by inducing ternary complex formation between an E3 ubiquitin ligase and a target protein. Despite their therapeutic potential, computational design of molecular glues remains largely u…
Low-Rank Adaptation (LoRA) has become a widely adopted technique for efficient neural network fine-tuning, decomposing model updates into low-rank matrices. However, LoRA remains computationally costly because it updates all matrices uniformly, regardless of their actual contribu…