Younghan Song, Bumsoo Park, Seungbae Jeon, Hyeokjin Kweon, Seungchul Lee, Jongbeom Na
Hanwen Wang, Yisha Zhang, Maxim Karrenbach, Yidan Ding, Bin He
Erin R. Claussen, Miles D Woodcock-Girard, Susan M. Fischer, Kevin Drew
Abstract Cellular function is driven by the activity of proteins in stable complexes. Protein complex assembly depends on the direct physical association of component proteins. Advances in macromolecular structure prediction with tools like AlphaFold and RoseTTAFold have greatly…
Hanpeng Liao, Chaofan Ai, Chen Liu, Hongbo Zhang, Dong Zhang, Pengfa Li, et al.
Recent work suggests that soil-borne viruses play an important role in controlling carbon (C) cycling and stocks. However, the contribution of individual prophage (i.e., temperate phages residing within bacterial hosts during lysogenic cycle) to C degradation remains largely undo…
Hoi Yee Chu, Chin Yu Mok, You-Rong Lin, Huawei Zhang, Takayuki Uchihashi, Shannon Wing Ngor Au
Abstract Cag type IV secretion system (CagT4SS) mediates the translocation of diverse substrates and is critical for the Helicobacter pylori pathogenesis. Its assembly is initiated by the central cylinder comprising CagX, CagY and CagM, however, the order and detailed mechanism r…
Parker Bassett, Binh A. Nguyen, Virender Singh, Patrick T. Garrett, James J. Moresco, Joshua Eddy, et al.
Immunoglobulin light chain (AL) amyloidosis is a systemic disorder caused by the misfolding and aggregation of free immunoglobulin light chains (LCs) secreted by abnormal plasma cells. The resulting amyloid fibrils deposit in multiple organs, leading to progressive dysfunction an…
Tamoghna Saha, Shichao Ding, Siyu Qin, Hannah Fishman, Rosie Pham, Te Gu, et al.
Abstract Biochemical analysis complements biophysical measurements by capturing the underlying molecular and metabolic changes that drive physiological health. Here, we introduce a compact, fully integrated smart ring capable of simultaneously monitoring multiple chemical biomark…