Breast cancer is one of the most widespread types of cancer, affecting approximately 8 million women worldwide. Electronic health records of patients diagnosed with this disease can serve as valuable datasets for computational analyses, enabling the discovery of new insights about the pathology. Unsupervised clustering, in particular, can identify groups of patients with medically significant features, revealing data trends that might otherwise go unnoticed by medical doctors. In this study, we first applied the DBSCAN density-based clustering method to three independent datasets derived from electronic medical records of patients with mammary carcinoma. Subsequently, to enhance our results, we preceded the DBSCAN application with a dimensionality reduction phase using UMAP. We evaluated our clustering outcomes using three statistical indices (DBCV, DCSI, and DISCO). Our results confirm the effectiveness of combining UMAP with DBSCAN for clustering data derived from electronic health records, paving the way for the medical interpretation of the patient groups identified by our approach.
In recent years, with the development of big data technology, increasingly more companies use HDFS for data processing and storage. As a result, the maintenance of distributed file systems has become an extremely important part of data management. As the function of server system…
Deep subspace clustering plays a critical role in applications involving multivariate spatiotemporal data, such as sea ice monitoring, disease spread analysis, and tracking neuro-degeneration over time. Despite recent advances, existing methods primarily rely on geometric self-ex…
Modeling shared and subject-specific structure in multisubject spatiotemporal data remains challenging, particularly in neuroimaging, where both spatial and temporal patterns exhibit rich variability across subjects. Existing matrix and tensor decompositions provide interpretable…
This paper studies the problem of stochastic variance reduction (SVR) for the maximum mean discrepancy (MMD) and correlation alignment (CORAL) loss functions. Although various offline SVR algorithms for these losses have been proposed, these are incompatible with online, distribu…
Autoregressive foundation models for electronic health records (EHRs) typically inherit pretraining methods from language modeling, where patient trajectories are concatenated into a single token stream and windows are sampled from that stream. In EHR data, this choice is consequ…
Autoregressive foundation models trained on tokenized electronic health records (EHRs) can support zero-shot clinical prediction, yet most operate on structured event codes alone, and do not incorporate multiple modalities in a principled way. We present a framework for condition…