RECIST diameter measurements are widely used for tumor response assessment, but they provide only a limited 2D description of lesion extent. We present LETT-NeXt, a lightweight RECIST-guided model that predicts 3D lesion masks from CT volumes and RECIST markers for the CVPR 2026 Foundation Models for Pan-cancer Segmentation in CT Images competition. LETT-NeXt extracts a RECIST-centered regional crop, encodes the RECIST line and endpoints as two prompt channels, and concatenates them with the CT input. A compact MedNeXt-v2 encoder--decoder predicts the lesion mask, followed by prompt-aware component selection and adaptive AutoZoom inference. On the public validation set, LETT-NeXt achieved a Dice Similarity Coefficient (DSC) of 79.4 $\pm$ 10.1 and a Normalized Surface Dice (NSD) of 72.3 $\pm$ 16.2. On the hidden test set, it achieved a DSC of 73.9 and an NSD of 67.3, corresponding to a challenge score of 70.6\%. On the public validation mirror, LETT-NeXt completed CPU inference in 6.9 $\pm$ 3.0 s per case with a peak memory use of 3.6 GB. Code is available at github.com/Ahus-AIM/lett-next.
Accurate segmentation of brain stroke lesions in non-contrast computed tomography (NCCT) scans is critical for rapid clinical decision-making, yet remains difficult due to the low contrast between lesion and normal brain tissue, heterogeneous lesion morphology across ischemic and…
3D point cloud-language models (3D-LLMs) enable 3D understanding by pairing point cloud encoders with large language models, but existing methods rely on costly multi-modal encoders (e.g., ULIP-2) that require image-text-point cloud alignment on 8x A100-scale compute, creating hi…
Large vision-language models are becoming increasingly dominant in 3D medical image interpretation, but we rarely know <i>which</i> internal units encode clinical findings or <i>where</i> that information lives in the representation. We first study this on a 3D chest vision-langu…
Satellite image editing requires spatially precise object-level control, but supervised editing datasets for overhead imagery are costly to build because object masks, semantic labels, and paired edits are rarely available at scale. We introduce SatEdit, a mask-conditioned satell…
Deep learning frameworks like nnU-Net achieve state-of-theart brain lesion segmentation performance but remain difficult to deploy in clinical research environments due to, among other reasons, software dependencies and computational requirements. We introduce StrokeSeg2, a light…
Large view synthesis models synthesize novel views through cross-view attention without explicit 3D representations, and recent studies have shown that they learn accurate spatial correspondence from RGB supervision alone. We observe that this correspondence generalizes beyond ap…